Connecting instruments to a computer with low latency has always been an issue, and the only place where Apple products have a significant advantage over Windows and Android. Windows wasn't designed for low latency, so interface makers have to come up with creative solutions that bypass windows, in this case ASIO drivers, but because they bypass windows they are not always the easiest to work with.
That's one barrier to entry and one that you can solve through your own expertise or a friend's.
The other issue is Internet latency. that really depends on your internet provider, distance to servers, and your own wiring (or lack thereof, using Wi-Fi will really kill your latency). While paying for higher internet speeds might help, internet service is more designed around speed to download large chunks of data (e.g. download a movie) rather than making tiny connections without delay. Gamers have been complaining about it for years (how long does the game server take to register that I clicked my mouse to fire my weapon, and how much delay is acceptable before I miss that headshot due to transmission delays).
I have used Jamulus with some friends. I work a hair better than Jamkazam but is geekier to set up, so as long as Jamkazam is free, it's probably the "best" solution.