I don't like Seymour Duncan pickups (yeah, so whip me). Early on in my endeavors I stuck with the obvious choices ... Seymour Duncan and Dimarzio. Without fail I always liked the Dimarzios better. That was a good 10 years ago and I haven't tried a Seymour Duncan since. Now that I have 16 electrics and every one of them tweaked to roll my personal socks up and down, my days of trying new pickups is pretty much over and done with. When it comes to humbuckers, all of my guitars save three have either GFS, Joe Naylor, Bare Knuckle or JWP pickups in them and those three have a set of Gibson '57 Classics, the stock pickups in my EPI 339 Pro, one Carvin with their original 11-pole-piece pickups. I will take Bare Knuckle or JWP over Duncan any day of the week (and don't ask me to start a range war by elucidating why ... just my personal preference). This is for dulal-bucker guitars.
For Strats I have tried just about every pickup out there and have landed on Zexcoils as the absolute best. Next in line would be Kinmans. I have never found a rail single-coil or stacked single-coil that I liked at all. Quarter-pounders are good for a loud, punchy, gutsy sound, but they don't sound like a Strat.